Thrombotic Complications at Altitude

Thrombotic complications of myeloma therapy.

Patients with multiple myeloma are at relatively high baseline risk of developing thromboembolic events (TEE), usually deep vein thromboses. There are numerous contributing factors, among them certain treatment regimens that include thalidomide or related compounds such as lenalidomide combined with glucocorticoids and/or cytotoxic chemotherapy. The risk of developing TEE appears to be particul...

Hypercoagulability and thrombotic complications in hemolytic anemias.

Cerebral Venous Sinus Thrombosis Masquerading as High Altitude Cerebral Edema at Extreme Altitude

Introduction: Extreme altitude travel has gained popularity globally for adventurous, scientific, and military endeavors. Cerebral venous sinus thrombosis (CVST) at extreme altitude is a rare, covert, and emergent condition requiring immediate intervention. Case Presentation: A case of CVST masqueraded as high altitude cerebral edema (HACE) at 6700 m/22000 ft i...

Athletes at High Altitude

CONTEXT Athletes at different skill levels perform strenuous physical activity at high altitude for a variety of reasons. Multiple team and endurance events are held at high altitude and may place athletes at increased risk for developing acute high altitude illness (AHAI). Training at high altitude has been a routine part of preparation for some of the high level athletes for a long time. Ther...

Medicine at high altitude

Medicine at high altitude provides important insights into the acute and chronic effects of hypoxia. Acute mountain sickness (AMS) is a common syndrome occurring after acute ascent to over 2,500 m and is caused by increased capillary permeability. A number of factors have been identified that increase the risk of AMS, in particular exercise. Avoiding rapid ascent, undue exercise and the use of ...